210569-76-9

Upstream product

• 39959-54-1 3-bromobenzylamine hydrochloride 
• 210569-71-4 <3-(6-bromo-3H-indol-3-yl)-propionylamino>-acetic acid 
• 226888-35-3 <3-(6-bromo-3H-indol-3-yl)-propionylamino>-acetic acid methyl ester 
• 226888-27-3 3-(6-bromo-3H-indol-3-yl)-acrylic acid methyl ester 
• 210889-33-1 3-(6-bromo-3H-indol-3-yl)-propionic acid methyl ester 
• 210569-69-0 3-(6-bromo-3H-indol-3-yl)-propionic acid 
• 17826-04-9 6-bromo-1H-indole-3-carbaldehyde 

Relevant academic research and scientific papers

Synthetic studies towards western and eastern macropolypeptide subunits of Kistamycin

The western subunit (fused bicyclic 16+15 membered ring) was synthesized by sequential intramolecular S(N)Ar reaction and the first 17-membered ring compound as model of the eastern subunit was obtained by an intramolecular Ni0 mediated coupling reaction.

The first synthesis of simplified 16- and 17-membered ring macropolypeptides containing the phenyl-indole system of Kistamycin and Chloropeptin I, II

The synthesis of simplified 16- and 17-membered ring macropolypeptides was achieved by Ni°mediated carbon-carbon ring closure of properly substituted linear precursors.