2106-50-5

Usage

Uses

Used in Agrochemical Industry:
2-Chloro-4-fluoronitrobenzene is used as an intermediate in the synthesis of various agrochemicals. Its unique chemical structure contributes to the development of effective pesticides and herbicides, enhancing crop protection and yield.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2-Chloro-4-fluoronitrobenzene serves as a key intermediate for the production of specific drugs. Its versatile chemical properties allow for the creation of medicinal compounds with targeted therapeutic effects.
Used in Dye Industry:
2-Chloro-4-fluoronitrobenzene is utilized as an intermediate in the manufacture of dyes. Its distinct molecular structure imparts color characteristics to various dye products, contributing to the vibrancy and stability of colors in different applications.

InChI:InChI=1/C6H3ClFNO2/c7-5-3-4(8)1-2-6(5)9(10)11/h1-3H

Upstream product

• 611-06-3 2,4-dichloronitrobenzene 
• 320-98-9 5-fluoro-2-nitrobenzoic acid 
• 625-98-9 3-chlorofluorobenzene 

Downstream Products

• 2106-02-7 2-chloro-4-fluoroaniline 
• 2369-11-1 5-fluoro-2-nitroaniline 
• 951666-45-8 N-butyl-5-fluoro-2-nitroaniline 
• 26039-74-7 Diethyl 2-(3-chloro-4-nitrophenyl)-2-methylmalonate 
• 1056619-65-8 6-(3-chloro-4-nitrophenoxy)-1H-indazole 
• 856452-73-8 1-(2-Chloro-4-nitro-phenyl)-1H-[1,2,4]triazole 
• 1235831-02-3 4-[5-(3-chloro-4-nitrophenoxy)-2-ethylphenyl]-2,2,6,6-tetramethylpyran-3,5-dione 
• 1007165-67-4 (3-(benzyloxy)phenyl)(3-chloro-4-nitrophenyl)sulfane 
• 1542259-21-1 2-chloro-N,N-dihexyl-4-nitroaniline 
• 1620477-15-7 C₂₀H₁₁ClN₄O₃ 

Relevant academic research and scientific papers

Decarboxylative Halogenation and Cyanation of Electron-Deficient Aryl Carboxylic Acids via Cu Mediator as Well as Electron-Rich Ones through Pd Catalyst under Aerobic Conditions

Simple strategies for decarboxylative functionalizations of electron-deficient benzoic acids via using Cu(I) as promoter and electron-rich ones by employing Pd(II) as catalyst under aerobic conditions have been established, which lead to smooth synthesis of aryl halides (-I, Br, and Cl) through the decarboxylative functionalization of benzoic acids with readily available halogen sources CuX (X = I, Br, Cl), and easy preparation of benzonitriles from decarboxylative cyanation of aryl carboxylic acids with nontoxic and low-cost K4Fe(CN)6 under an oxygen atmosphere for the first time.

HOMOGENEOUS TIME RESOLVED FLUORESCENCE BASED TEST SYSTEM

The present invention concerns a fluorescence resonance energy transfer based high throughput test system to measure the formation of the HIV gp41 six-helix bundle. In a first embodiment the current invention relates to a homogeneous time resolved fluorescence-based test system comprising a first helical polypeptide consisting essentially of the sequence of IQN36 (SEQ ID NO:1); a second helical polypeptide consisting essentially of the sequence of C34 (SEQ ID NO: 2) wherein said IQN36 is labeled with a light emitting fluorophore and said C34 is labeled with an ultra-violet excitable fluorophore.

Kepner-Tregoe decision analysis as a tool to aid route selection. Part 2. Application to AZD7545, a PDK inhibitor

Kepner-Tregoe decision analysis was formally used as an aid to route selection, as outlined in the preceding paper. Over 40 paper routes were assessed for suitability for both immediate and longer term manufacture of AZD7545, a compound in the early stages of development. Eight routes were then investigated in full in the laboratory, and a further four in part, over a period of 3-4 months. From this exercise, the preferred long-term manufacturing route was identified before the first pilot scale manufacture had been completed. This route selection exercise worked well in this case where a large number of potential routes had to be considered using limited resources. It was also an effective means of bringing some long-term manufacturing issues to the fore at an early stage in development.

Efficient phosphorus catalysts for the halogen-exchange (Halex) reaction

New families of monomeric to dendritic, and monocationic to multicationic (PNP) compounds have been prepared and tested as catalysts in halogen exchange (Halex) reactions. Some of them allow an increase in the efficiency of these reactions which are performed in some cases under the mildest conditions reported up to now.

Tetramethylammonium chloride as a selective and robust phase transfer catalyst in a solid-liquid halex reaction: The role of water

Tetramethylammonium chloride (TMAC) is an effective phase transfer catalyst for the selective chloride/fluoride exchange reaction of activated aryl chlorides with potassium fluoride provided that the amount of water in the system is limited and controlled.

Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers

Salts of compounds of the formula STR1 wherein X is a hydrogen atom, a halogen atom, a trihalomethyl group, an alkyl group, or a cyano group, and Y is a hydrogen atom, a halogen atom, or a trihalomethyl group, and compositions containing these salts exhibit herbicidal activity.

Herbicidal 4-trifluoromethyl-3'-oxygen-substituted-4'-substituted diphenyl ethers

The herbicidal 4-trifluoromethyl-3'-oxygen-substituted-4'-substituted diphenyl ethers comprise a class of compounds that are highly effective herbicides.

Herbicidal 4-trifluoromethyl-3'-carbon-substituted-4'-substituted diphenyl ethers

The herbicidal-4-trifluoromethyl-3'-carbon-substituted-4'-substituted diphenyl ethers comprise a class of compounds that are highly effective herbicides.

Herbicidal 4-trifluoromethyl-3'-nitrogen-substituted-4'-substituted diphenyl ethers

The herbicidal 4-trifluoromethyl-3'-nitrogen-substituted-4'-substituted diphenyl ethers comprise a class of compounds that are highly effective herbicides.

Herbicidal 4-trifluoromethyl 4-nitrodiphenyl ethers

Compounds of the formula STR1 wherein X is a cyano group, Y is a hydrogen atom, a halogen atom, or a trihalomethyl group, and Z is a substituted alkoxy group, and compositions containing these compounds exhibit herbicidal activity.