210836-73-0Relevant academic research and scientific papers
DIHYDROPYRIMIDONE DERIVATIVES AS NPY ANTAGONISTS
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, (2008/06/13)
The present invention provides a series of non-peptidergic antagonists of NPY comprising piperidine derivatives of 4-phenyl-1,4-dihydropyrimidinones of the Formula I STR1 wherein R, R 1 and R. sup.2 are defined herein. As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.
