21096-43-5Relevant academic research and scientific papers
An efficient and one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles catalyzed by InCl3·3H2O
Das Sharma, Saikat,Hazarika, Parasa,Konwar, Dilip
, p. 2216 - 2220 (2008)
InCl3·3H2O was found to be a mild and effective catalyst for the efficient, one-pot, three component synthesis of 2,4,5-trisubstituted imidazoles at room temperature. Moreover, the utility of this protocol was further explored conveniently for the one-pot, four component synthesis of 1,2,4,5-tetrasubstituted imidazoles in high yields.
Synthesis of 2,4,5-trisubstituted imidazoles catalyzed by [Hmim]HSO 4 as a powerful Broensted acidic ionic liquid
Khosropour, Ahmad R.
, p. 264 - 269 (2008/09/19)
An efficient and green procedure for the synthesis of 2,4,5-trisubstituted imidazoles with various aldehydes using a catalytic amount of 1-methylimidazolium hydrogenesulfate as an active and low cost Broensted acidic room temperature ionic liquid has been developed. The ionic liquid was easily separated from the reaction mixture and was recycled five times without any loss in activity.
