210962-09-7

Basic information

• Product Name: 1-(4-PYRIDINYL)-4-PIPERIDINECARBOXYLIC
• Synonyms: 1-(4-PYRIDINYL)-4-PIPERIDINECARBOXYLIC;1-(4-Pyridinyl)-4-piperidinecaboxylic acid monohydrochloride;1-(4-Pyridinyl)-4-piperidinecaboxylic acid Monohydrochloride,98%;1-(Pyridin-4-yl)piperidine-4-carboxylic acid hydrochloride;3,4,5,6-Tetrahydro-2H-[1,4']bipyridinyl-4-carboxylic acid hydrochloride;1-(4-Pyridinyl)-4-piperidinecaboxylic acid monohydrochloride 98%
• CAS NO: 210962-09-7
• Molecular Formula: C11H14N2O2.ClH
• Molecular Weight: 242.704
• Product Categories: Building Blocks;Heterocyclic Building Blocks;Piperidines
• Mol File: 210962-09-7.mol

Chemical Properties

• Melting Point: 223-226 °C(lit.)
• Boiling Point: 431.5°C at 760 mmHg
• Flash Point: 214.7°C
• Appearance: /
• Vapor Pressure: 3.28E-08mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 1-(4-PYRIDINYL)-4-PIPERIDINECARBOXYLIC(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-PYRIDINYL)-4-PIPERIDINECARBOXYLIC(210962-09-7)
• EPA Substance Registry System: 1-(4-PYRIDINYL)-4-PIPERIDINECARBOXYLIC(210962-09-7)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 210962-09-7(Hazardous Substances Data)

Usage

Uses

Reactant for synthesis of Xa inhibitors and anticoagulants

InChI:InChI=1/C11H14N2O2.ClH/c14-11(15)9-3-7-13(8-4-9)10-1-5-12-6-2-10;/h1-2,5-6,9H,3-4,7-8H2,(H,14,15);1H

Upstream product

• 121912-29-6 1-(pyridin-4-yl)piperidine-4-carboxylic acid ethyl ester 

Downstream Products

• 168077-29-0 1-(4-pyridinyl)piperidin-4-yl carbonyl chloride 

Relevant articles and documents

BENZAMIDINE DERIVATIVES

A benzamidine derivative of the following formula, analogs thereof and pharmaceutically acceptable salts thereof have an effect of inhibiting the blood coagulation based on their excellent effect of inhibiting activated blood-coagulation factor X. Thus, a blood-coagulation inhibitor or an agent for preventing or treating thrombosis or embolism, containing one of those compounds as the active ingredient, is provided.

Benzamidine derivatives

Benzamidine derivatives of the following formula, analogs thereof and pharmaceutically acceptable salts thereof are provided. These compounds have an effect of inhibiting activated blood-coagulation factor X, and they are useful as agents for preventing or treating various diseases caused by thrombi or emboli.

AMINOISOQUINOLINE DERIVATIVES

Aminoisoquinoline derivatives represented by formulae (I and II), analogs thereof or pharmaceutically acceptable salts of the same. Because of having excellent inhibitory effects on activated blood coagulation factor X, these compounds are useful as active ingredients in anticoagulants or preventives/remedies for thrombosis or embolism.

BENZAMIDINE DERIVATIVES

Benzamidine derivatives of the following formulae or analogs thereof, i. e., pharmaceutically acceptable salts thereof, are provided. These compounds or salts thereof have a blood-coagulation inhibiting effect based on an excellent effect of inhibiting the action of activated blood coagulation factor X, and they are useful as anticoagulants.