210963-78-3

Usage

Uses

Used in Scientific Research:
4-[(dimethylamino)iminomethyl] benzoic acid HCL is used as a research chemical for conducting various chemical reactions and experiments. Its unique molecular structure and bonding make it a valuable compound for studying chemical properties and interactions.
Used in Pharmaceutical Industry:
4-[(dimethylamino)iminomethyl] benzoic acid HCL is used as an intermediate or building block in the synthesis of pharmaceutical compounds. Its presence in benzoic acids and derivatives class allows it to be a potential candidate for the development of new drugs and therapeutic agents.
Used in Chemical Reactions:
4-[(dimethylamino)iminomethyl] benzoic acid HCL is used as a reactant in various chemical reactions, where its properties and reactivity contribute to the formation of new compounds or the modification of existing ones.
Precautionary Measures:
When handling 4-[(dimethylamino)iminomethyl] benzoic acid HCL, it is essential to follow safety protocols, as it may be harmful if swallowed, inhaled, or comes in contact with the skin. Additionally, it could be potentially corrosive to metals, so proper storage and handling procedures should be implemented to prevent any adverse effects.

Upstream product

• 506-59-2 N,N-dimethylammonium chloride 
• 7153-22-2 ethyl 4-cyanobenzoate 

Downstream Products

• 1639024-44-4 C₃₅H₄₅N₇O₆ 

Relevant academic research and scientific papers

Preparation method of betrexiban intermediate compound

The present invention belongs to the field of drug synthesis technology, specifically relates to a method for preparing a betroxiban intermediate, the present invention prepares a method of preparing a betroxiban intermediate comprising: dissolving compound II in an organic solvent A, temperature-controlled drops plus tert-butyl dimethylsilane, drip bi, insulation reaction, TLC detection, reaction completed, dropwise addition of dimethylamino lithium solution to the reaction solution, dropwise addition, continue insulation reaction, TLC detection, reaction completion, adding ethyl acetate dilution, adding saturated ammonium chloride solution to the reaction solution wash, The organic phase is dried with anhydrous sodium sulfate, concentrated to dry under reduced pressure to obtain compound III; to provide a new method of using p-cyanobenzoic acid as raw material, using silanization reagents to protect the hydroxyl group, and obtaining a key intermediate of betroxiban, which has fewer synthetic route steps, high yield and high purity.

Preparation method of beta-caraban

The preparation method comprises the following steps: in liquid dimethylamine, a compound of the structural formula II or a salt thereof and MN (CH). 3 )2 The dimethylamine solution in the structural formula I is reacted to obtain the fritilth. M represents Li or MgX; and M is Li or Na. Wherein X is selected from one of Cl, Br and I. The preparation method disclosed by the invention is high in yield and high in product purity, can substantially avoid generation of single methyl ammonia impurities and dechlorination impurities, and greatly simplifies the subsequent refining process. In addition, the preparation method is single in solvent, the use of the mixed solvent is avoided, the later-stage solvent recovery is convenient, and the three wastes can be reduced.