210964-81-1

Basic information

• Product Name: 4-Oxazolemethanol, 2,2'-(1-methylethylidene)bis[4,5-dihydro-5-phenyl-, (4S,4'S,5S,5'S)-
• CAS NO: 210964-81-1
• Molecular Formula: C23H26N2O4
• Molecular Weight: 394.47
• Mol File: 210964-81-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-Oxazolemethanol, 2,2'-(1-methylethylidene)bis[4,5-dihydro-5-phenyl-, (4S,4'S,5S,5'S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Oxazolemethanol, 2,2'-(1-methylethylidene)bis[4,5-dihydro-5-phenyl-, (4S,4'S,5S,5'S)-(210964-81-1)
• EPA Substance Registry System: 4-Oxazolemethanol, 2,2'-(1-methylethylidene)bis[4,5-dihydro-5-phenyl-, (4S,4'S,5S,5'S)-(210964-81-1)

Safety Data

• Hazardous Substances Data: 210964-81-1(Hazardous Substances Data)

Upstream product

• 7321-55-3 2,2-dimethylmalononitrile 
• 28143-91-1 (1S,2S)-2-amino-1-phenyl-1,3-diol 

Downstream Products

• 1196974-64-7 (4'S,5'S)-2,2-bis[4'-(triisopropylsilyl)-oxymethy-5'-phenyl-1',3'-oxazolin-2'-yl]propane 

Relevant articles and documents

New bis(oxazoline) ligands with secondary binding sites for the asymmetric cyclopropanation of furans

The diastereo- and enantioselective cyclopropanation of furans was achieved in up to 91% ee using a new set of chiral bis(oxazoline) ligands that are able to use secondary binding sites to enhance selectivity. In contrast, with substrates such as styrene

New applications of bis(oxazoline) ligands in catalysis: Asymmetric 1,2-and 1,4-addition of ZnR2 to carbonyl compounds

(Matrix Presented) The enantioselective addition of ZnR2 to aldehydes (1,2) and cyclic enones (1,4) was accomplished using bis(oxazolines) as chiral ligands. The requirement for hydroxymethylene side chains in the ligands strongly suggests that bimetallic catalysts are decisive for high enantiocontrol in these additions.