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2-(4-m-tolyl-piperazin-1-yl)-ethylamine is a chemical compound characterized by the molecular formula C14H22N2. It is an alkylamine derivative that features a piperazine ring and a 4-methyltoluene group. 2-(4-m-tolyl-piperazin-1-yl)-ethylamine is of interest in the pharmaceutical sector due to its potential as a serotonin and norepinephrine reuptake inhibitor, suggesting its utility in addressing conditions like depression and anxiety. Additionally, it may serve as a valuable chemical building block or intermediate in research settings. While ongoing studies are further exploring its properties and applications, 2-(4-m-tolyl-piperazin-1-yl)-ethylamine already shows promise for a range of therapeutic and scientific uses.

21103-27-5

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21103-27-5 Usage

Uses

Used in Pharmaceutical Industry:
2-(4-m-tolyl-piperazin-1-yl)-ethylamine is used as a potential therapeutic agent for the treatment of conditions such as depression and anxiety. Its role as a serotonin and norepinephrine reuptake inhibitor suggests that it could help regulate mood and alleviate symptoms associated with these disorders.
Used in Research:
2-(4-m-tolyl-piperazin-1-yl)-ethylamine is used as a chemical building block or intermediate in scientific research. Its unique structure and functional groups make it a candidate for the development of new compounds and pharmaceuticals, contributing to the advancement of drug discovery and chemical synthesis methodologies.

Check Digit Verification of cas no

The CAS Registry Mumber 21103-27-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,1,0 and 3 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 21103-27:
(7*2)+(6*1)+(5*1)+(4*0)+(3*3)+(2*2)+(1*7)=45
45 % 10 = 5
So 21103-27-5 is a valid CAS Registry Number.

21103-27-5Relevant academic research and scientific papers

Chemical modifications on 4-arylpiperazine-ethyl carboxamide derivatives differentially modulate affinity for 5-HT1A, D4.2, and α2A receptors: Synthesis and in vitro radioligand binding studies

Graulich, Amaury,Lonard, Marc,Rsimont, Mlissa,Huang, Xi-Ping,Roth, Bryan L.,Ligeois, Jean-Franois

experimental part, p. 56 - 67 (2010/05/18)

A series of substituted 4-aryl-piperazine-ethyl heteroarylcarboxamides were prepared and tested in in vitro radioligand binding studies. The presence of a quinoxaline has a favourable impact in terms of serotonin 5-HT1A versus dopamine D4.2 receptor selectivity. Compounds with a 3-CF3 group at the distal phenyl ring are the most effective in terms of affinity and selectivity for 5-HT1A versus D4.2 receptors. A 4-phenyl-1,2,3,6- tetrahydropyridine in place of the corresponding 4-phenyl-piperazine side chain is also favourable not only for the affinity for 5-HT1A and D4.2 receptors but also in some cases for α2A-adrenoceptors.

Synthesis and biological evaluation of oxazole derivatives as T-type calcium channel blockers

Lee, Jie Eun,Koh, Hun Yeong,Seo, Seon Hee,Baek, Yi Yeon,Rhim, Hyewhon,Cho, Yong Seo,Choo, Hyunah,Pae, Ae Nim

scheme or table, p. 4219 - 4222 (2010/09/04)

T-type calcium channel is one of therapeutic targets for the treatment of cardiovascular diseases and neuropathic pain. In this study, as a part of our ongoing efforts to develop potent T-type calcium channel blockers, we designed oxazole derivatives subs

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