211105-11-2

Upstream product

• 32454-24-3 2-methyl-2-p-tolyl-propionic acid ethyl ester 

Downstream Products

• 174483-06-8 ethyl 4-[4[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylbenzeneacetate 
• 207301-64-2 2-[4-(3-[1,3]Dioxolan-2-yl-1-hydroxy-propyl)-phenyl]-2-methyl-propionic acid ethyl ester 
• 207301-40-4 2-[4-(3-[1,3]Dioxolan-2-yl-propionyl)-phenyl]-2-methyl-propionic acid ethyl ester 
• 83799-24-0 fexofenadine 
• 207301-59-5 2-(4-Chlorocarbonyl-phenyl)-2-methyl-propionic acid ethyl ester 

Relevant academic research and scientific papers

An efficient and facile synthesis of racemic and optically active fexofenadine

In efficient and practical method for the synthesis of racemic and optically active (96% ee) fexofenadine is described. The key racemic or optically active lactol intermediate 2 is prepared from readily available tolyl derivative 3.