21115-69-5Relevant academic research and scientific papers
ANTI-VIRAL COMPOUNDS
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Paragraph 00318, (2018/09/18)
Described herein are compounds and related compositions for the treatment of viral infections, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells,including compounds that can activate the RIG-I pathway.
Facile synthesis of thioamides via P2S5-mediated beckmann rearrangement of oximes
Li, Jiangsheng,Cheng, Chao,Zhang, Xinrui,Li, Zhiwei,Cai, Feifei,Xue, Yuan,Liu, Weidong
, p. 1687 - 1689 (2012/10/29)
A facile and efficient approach to the synthesis of secondary thioamides from ketoximes via Beckmann rearrangement has been established, using phosphorus pentasulfide as a dehydrating and thiating agent. It is also efficient for the preparation of primary thiobenzamide from benzaldoxime. This approach features simple-operation, easy-control and good to excellent yields.
Ketoximes to N-substituted thioamides via PSCl3 mediated Beckmann rearrangement
Pathak, Uma,Pandey, Lokesh Kumar,Mathur, Sweta,Suryanarayana
scheme or table, p. 5409 - 5411 (2009/12/08)
N-Substituted thioamides were accessed from ketoximes by utilising PSCl3 as a uniquely capable reagent to induce Beckmann rearrangement as well as to capture the intermediate nitrilium ion. The Royal Society of Chemistry 2009.
