211188-23-7Relevant academic research and scientific papers
Aziridine mediated asymmetric synthesis of α-benzylserine and α-n-butylserine
Davis, Franklin A,Zhang, Yulian,Rao, Ashwin,Zhang, Zhijun
, p. 6345 - 6352 (2007/10/03)
Regioselective hydrogenolysis of enantiopure 2-benzyloxyaziridine 2-carboxylates represents a general method for the asymmetric synthesis of α-substituted serines. The aziridines are readily prepared via an aza-Darzens reaction of the enolate of methyl 3-
Stereoselective synthesis of α-substituted serines from protected erythrulose oximes
Carda,Murga,Rodriguez,Gonzalez,Castillo,Marco
, p. 1703 - 1712 (2007/10/03)
The additions of organolithium reagents to the C=N bond of several chiral oxime ethers derived from erythrulose afforded protected amino polyols with high diastereoselectivity. Four of the latter compounds have been convened into the α,α-disubstituted α-amino acids (R)-2-(-)-methylserine, (S)-2-(+)-methylserine, (R)-(+)-2-phenylserine and (R)-(-)-2-n-butylserine.
