211448-04-3Relevant articles and documents
Asymmetric Diels-Alder reactions of 2-fluoroacrylic acid derivatives. Part 2: A remarkable effect of fluorine substituent on the diastereoselectivity
Ito, Hisanaka,Saito, Akio,Taguchi, Takeo
, p. 1989 - 1994 (1998)
An efficient construction of a chiral monofluorinated tertiary carbon was achieved by a highly exo- and diastereofacial selective Diels-Alder reaction of a 2-fluoroacrylic acid derivative derived from 8-phenylmenthol, and cyclopentadiene. The substituent effect of the fluorine on the selectivities is remarkable as compared with the other substituents at the α-position of the acrylate.
Synthesis of 2-fluoro analog of 6-aminonorbornane-2,6-dicarboxylic acid: A conformationally rigid glutamic acid derivative
Ito, Hisanaka,Saito, Akio,Kakuuchi, Akito,Taguchi, Takeo
, p. 12741 - 12750 (2007/10/03)
Synthesis of 2-fluoro analog of 6-aminonorbornane-2,6-dicarboxylic acid, a conformationally restricted analog of glutamic acid, in optically pure form is described.