21148-60-7

Upstream product

• 1685-33-2 N-[(benzyloxy)carbonyl]-D-valine 
• 2812-46-6 proline tert-butyl ester 

Downstream Products

• 6021-07-4 N-(benzyloxycarbonyl)threonyl-D-valylproline t-butyl ester 
• 73984-45-9 (2S,3S)-1-(2-nitro-3-benzyloxy-4-methylbenzoyl)-3-methyl-2-aziridinecarbonyl-D-valylproline t-butyl ester 
• 73984-43-7 (2S,3S)-1-trityl-3-methyl-2-aziridinecarbonyl-D-valylproline t-butyl ester 

Relevant academic research and scientific papers

Studies on 2-Aziridinecarboxylic Acid.IV.Total Synthesis of Actinomycin D (C1) via Ring-opening Reaction of Aziridine

Actinomycin D (C1) has been synthesized by a route involving the ester formation between two peptide fragments, (2S,3S)-1-(2-nitro-3-benzyloxy-4-methylbenzoyl)-3-methyl-2-aziridiecarbonyl-D-valylproline t-butyl ester and N-benzyloxycarbonylsarc