211491-21-3Relevant academic research and scientific papers
Copper-catalyzed (4+1) and (3+2) cyclizations of iodonium ylides with alkynes
Liang, Hao,He, Xiaobo,Zhang, Yaqi,Chen, Bin,Ouyang, Jia-Sheng,Li, Yongsu,Pan, Bendu,Subba Reddy, Chitreddy V.,Chan, Wesley Ting Kwok,Qiu, Liqin
supporting information, p. 11429 - 11432 (2020/10/12)
The copper(ii)-catalyzed (4+1) cyclizations and copper(i)-catalyzed (3+2) cycloadditions of iodonium ylides and alkynes were successfully developed by employing efficient and safe iodonium ylides instead of traditional diazo compounds. Highly functionaliz
Iron-catalyzed oxidative coupling of terminal alkynes with arylboronic acids
You, Xiu L.,Xu, Lai,Hu, Tao
experimental part, p. 300 - 304 (2012/07/14)
Abstract: Iron-catalyzed cross-coupling of terminal alkynes with arylboronic acids under mild conditions has been developed. Although the reaction gave only moderate yields, the advantage of this method was its use of convenient and inexpensive iron catal
A Suzuki-type cross-coupling reaction of arylacetylene halides with arylboronic acids
Shi, Yu,Li, Xiaoyu,Liu, Jianhui,Jiang, Wenfeng,Sun, Licheng
experimental part, p. 514 - 520 (2012/04/04)
A PdCl2-catalyzed direct alkynylation of arylboronic acids to give diarylacetylenes is described. The optimal conditions using PdCl 2 as catalyst, MeOH-PhMe-H2O as solvent and K 2CO3 as base effectively suppressed the formation of homo-coupling product and afforded moderate to good yield of the desired unsymmetrical coupling product. This reaction represents a Suzuki-type sp 2(C-B)-sp(C-X) cross-coupling. Copyright
PdCl2-catalyzed cross-coupling reaction of arylacetylene iodides with arylboronic acids to diarylacetylenes
Shi, Yu,Li, Xiaoyu,Liu, Jianhui,Jiang, Wenfeng,Sun, Licheng
supporting information; experimental part, p. 3626 - 3628 (2010/08/13)
A new Suzuki-type cross-coupling reaction between 1-iodo-2-arylalkynes and arylboronic acids to afford a wide variety of functionalized diarylacetylenes in a mild reaction condition was developed. The reaction was catalyzed by a small amount of a structurally simple, commercially available, and stable PdCl 2. This unique sp-sp2 carbon-carbon bond formation provides a new protocol for the synthesis of diarylacetylenes, which is a new addition to the Suzuki cross-coupling reaction.
Palladium-catalyzed cyclization of o-alkynylphenols with allyl carbonates. A regioselective synthesis of 2-substituted-3-allylbenzo[b]furans
Cacchi, Sandro,Fabrizi, Giancarlo,Moro, Leonardo
, p. 741 - 745 (2007/10/03)
2-Substituted-3-allylbenzo[b]furans 3 can be prepared from o-alkynylphenols 1 and allyl carbonates 2 through a palladium-catalyzed O-allylation/cyclization sequence. Two basic procedures have been developed: a stepwise method based on the isolation of O-allyl derivatives 4 and their subsequent cyclization to 3 (procedure A) and a one-pot reaction omitting the isolation of 4 (procedure B). The cyclization of 4 in the presence of the electron-rich sterically-encumbered ligand tris(2,4,6-trimethoxyphenyl)phosphine (ttmpp) exhibits remarkable regioselectivity in that 3-allylbenzofurans in which the benzofuryl unit is bound to the less substituted allyl terminus are formed almost exclusively. Some loss of the stereochemistry of the carbon-carbon double bond is observed.
