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Gamma-amanitin, also known as amatoxin, is a highly toxic cyclic octapeptide found in the poisonous mushroom Amanita phalloides, commonly referred to as the death cap mushroom. It exerts its toxicity by inhibiting RNA polymerase II, which leads to the cessation of protein synthesis and ultimately results in cell death. gamma-amanitin's high toxicity and the absence of a specific antidote make it a critical concern in cases of mushroom poisoning, with even a small amount capable of causing severe liver damage and potentially being fatal if not treated promptly.

21150-23-2

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21150-23-2 Usage

Uses

Used in Research Applications:
Gamma-amanitin is utilized as a research tool for studying the function and regulation of RNA polymerase II. Its specific inhibition of this enzyme allows scientists to investigate the role of RNA polymerase II in various cellular processes and to understand the mechanisms of action of other compounds that may affect this enzyme.
Used in Toxicological Studies:
Due to its extreme toxicity, gamma-amanitin is employed in toxicological research to explore the effects of potent toxins on biological systems. This helps in developing a better understanding of the mechanisms of toxicity and potential treatments or antidotes for poisoning incidents.
Used in Educational Contexts:
Gamma-amanitin serves as a cautionary example in educational settings to illustrate the dangers of consuming wild mushrooms without proper identification. It is used to teach about the importance of recognizing toxic species and the severe consequences of misidentification.

Check Digit Verification of cas no

The CAS Registry Mumber 21150-23-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,1,5 and 0 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 21150-23:
(7*2)+(6*1)+(5*1)+(4*5)+(3*0)+(2*2)+(1*3)=52
52 % 10 = 2
So 21150-23-2 is a valid CAS Registry Number.

21150-23-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name γ-Amanitin

1.2 Other means of identification

Product number -
Other names Gamma-Amanitin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:21150-23-2 SDS

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