211504-67-5Relevant academic research and scientific papers
An enantioselective synthetic strategy toward the polyhydroxylated agarofuran
Zhou, Gang,Gao, Xiaolei,Li, Weidong Z.,Li, Yulin
, p. 3101 - 3103 (2001)
This paper describes a new approach for the enantioselective syntheses of naturally occurring polyhydroxylated dihydroagarofuran sesquiterpenoids starting from (-)-carvone. Through utilizing asymmetric Robinson annulation and acetoxylation as key steps, the agarofuran skeleton was enantioselectively constructed and an oxyfunctionalized group was introduced into the C-1 position. The important intermediate 23 to dihydroagarofuran was obtained in eleven steps.
