211511-70-5

Upstream product

• 2937-50-0 Allyl chloroformate 
• 211511-69-2 5-Bromomethyl-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 126114-07-6 tert-butyl 5-(hydroxymethyl)-3,6-dihydro-1(2H)-pyridinecarboxylate 
• 244267-39-8 (1-Benzyl-1,2,5,6,tetrahydro-pyridin-3-yl)-methanol 
• 211511-68-1 N-methoxycarbonyl-3-hydroxymethyl-1,2,5,6-tetrahydropyridine 
• 100-55-0 3-hydroxymethylpyridin 

Downstream Products

• 211511-73-8 5-[(Z)-(R)-2-Allyloxycarbonylamino-8-(toluene-4-sulfonyloxy)-oct-3-enyl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Stereoselective synthesis of the tetracyclic core of manzamine via the vinylogous amide photocycloaddition cascade

The stereoselective preparation of the tetracyclic core of the manzamine alkaloids via the intramolecular vinylogous amide photocycloaddition/retro- Mannich fragmentation/Mannich closure cascade is described. The striking effect of unsaturation in the eight-membered ring on the stereoselectivity of the cycloaddition and a computational analysis of these results are presented.