211564-07-7

Upstream product

• 99-59-2 3-amino-4-methoxynitrobenzene 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1604803-41-9 (2-methoxy-5-nitro-4-trimethylsilanylmethylphenyl)carbamic acid tert-butyl ester 
• 1604803-44-2 {4-[(E)-2-(4-iodo-2-methoxypyridin-3-yl)vinyl]-2-methoxy-5-nitrophenyl}carbamic acid tert-butyl ester 
• 1604803-43-1 trifluoroacetic acid 2-(4-tert-butoxycarbonylamino-5-methoxy-2-nitrophenyl)-1-(4-iodo-2-methoxypyridin-3-yl)ethyl ester 
• 1604803-42-0 {4-[2-hydroxy-2-(4-iodo-2-methoxypyridin-3-yl)ethyl]-2-methoxy-5-nitrophenyl}carbamic acid tert-butyl ester 
• 312300-45-1 1,1-dimethylethyl [5-amino-2-(methyloxy)phenyl]carbamate 

Relevant academic research and scientific papers

6-AMINOINDOLE DERIVATIVES AS TRP CHANNEL ANTAGONISTS

The invention is concerned with the compounds of formula (I) and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical composition

2- [ (2-{PHENYLAMINO}-1H-PYRROLO [2, 3-D] PYRIMIDIN-4-YL) AMINO] BENZAMIDE DERIVATIVES AS IGF-1R INHIBITORS FOR THE TREATMENT OF CANCER

Novel pyrrolopyrimidines as shown in formula (I) and pharmaceutically acceptable derivatives thereof. The compounds are useful in the inhibition of IGF-1R.

Cell proliferation inhibitors

Compounds having formula (I) inhibit cellular proliferation. Processes for the preparation of the compounds, pharmaceutical compositions containing the compounds, and methods of treatment using the compounds are disclosed.