21157-12-0

Basic information

• Product Name: BOC-HYP-OH DCHA
• Synonyms: Boc-trans-4-hydroxy-L-proline dicyclohexylamine salt;N-T-BOC-L-HYDROXYPROLINEDICYCLOHEXYLAMMO NIUM;(2S,4R)-1-tert-butoxycarbonyl-4-hydroxy-proline;(2S,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid;Boc-trans-4-hydroxy-L-proline dicyclohexylamine sa;Boc-Hyp-OH·DCHA Boc-trans-4-hydroxy-L-proline dicyclohexylaMine salt;DicyclohexylaMine (2S,4R)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate;DicyclohexylaMine trans-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate
• CAS NO: 21157-12-0
• Molecular Formula: C22H40N2O5
• Molecular Weight: 412.56
• Mol File: 21157-12-0.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 390.9 °C at 760 mmHg
• Flash Point: 190.2 °C
• Appearance: /
• Vapor Pressure: 9.99E-08mmHg at 25°C
• Storage Temp.: Store at 0-5°C
• CAS DataBase Reference: BOC-HYP-OH DCHA(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-HYP-OH DCHA(21157-12-0)
• EPA Substance Registry System: BOC-HYP-OH DCHA(21157-12-0)

Safety Data

• Hazardous Substances Data: 21157-12-0(Hazardous Substances Data)

Usage

Description

BOC-HYP-OH DCHA, also known as Dicyclohexylamine trans-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate, is a white powder chemical compound with significant applications in the pharmaceutical industry. Its unique structure and properties make it a valuable component in the development of various drugs and therapeutic agents.

Uses

Used in Pharmaceutical Industry:
BOC-HYP-OH DCHA is used as a key intermediate in the synthesis of Pleuromutilin Alkoxycarbonyl Carbamate derivatives, which are potent antibacterial agents. These derivatives exhibit broad-spectrum antibacterial activity and are effective against both Gram-positive and Gram-negative bacteria, including drug-resistant strains.
The compound's role in the preparation of these derivatives is crucial, as it contributes to the development of new and improved antibiotics to combat the growing threat of antibiotic resistance.

InChI:InChI=1/C12H23N.C10H17NO5/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12;1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h11-13H,1-10H2;6-7,12H,4-5H2,1-3H3,(H,13,14)/t;6-,7+/m.1/s1