211632-75-6Relevant academic research and scientific papers
Simple fragment syntheses of all four isomers of the spermine alkaloid kukoamine
Karigiannis, George,Mamos, Petros,Balayiannis, George,Katsoulis, Ioannis,Papaioannou, Dionissios
, p. 5117 - 5120 (2007/10/03)
All four isomers of the spermine alkaloid kukoamine were unambiguously prepared through diacylation with O,O'-dibenzylcasseyl chloride of suitably protected (benzyl and/or trityl groups) spermine derivatives, assembled on solid and/or in liquid phase using β-alanine and γ-aminobutyric acid, followed by simultaneous N- and O- deprotection and double bond reduction using catalytic hydrogenation.
