21168-71-8

Usage

Uses

Used in Pharmaceutical Industry:
C-(1-Ethyl-piperidin-4-yl)-methylamine is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be incorporated into a wide range of drug molecules, contributing to the development of new therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, C-(1-Ethyl-piperidin-4-yl)-methylamine serves as an essential component in the production of certain agrochemicals. Its ability to form stable compounds makes it suitable for use in the development of effective and safe pesticides and other agricultural products.
Used in Organic Synthesis:
C-(1-Ethyl-piperidin-4-yl)-methylamine is utilized as a versatile intermediate in the synthesis of other organic compounds. Its reactivity and functional groups enable the formation of various chemical entities, expanding the scope of organic chemistry and its applications.
As a clear, colorless liquid with a faint odor, C-(1-Ethyl-piperidin-4-yl)-methylamine should be handled with care due to its potential health and safety hazards. Its applications across different industries highlight the importance of C-(1-ETHYL-PIPERIDIN-4-YL)-METHYLAMINE in modern chemical research and development.

InChI:InChI=1/C8H18N2/c1-2-10-5-3-8(7-9)4-6-10/h8H,2-7,9H2,1H3

Upstream product

• 77445-06-8 1-acetyl-4-aminomethylpiperidine 

Downstream Products

• 1347636-13-8 1-[1-(4-Fluorophenethyl)piperidin-4-yl]-6-(1-ethylpiperidin-4-yl)methylcarbamoylmethylindole oxalate 
• 1266620-21-6 C₁₆H₂₁ClFN₃O₂ 
• 1331742-47-2 C₂₀H₂₃F₃N₆O 
• 1192166-28-1 4-(8-Dimethylamino-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydro-pteridin-2-ylamino)-N-(1-ethyl-piperidin-4-ylmethyl)-3-methoxy-benzamide 
• 1025065-78-4 N-((1-ethylpiperidin-4-yl)methyl)-7-methyl-3-(3-(trifluoromethoxy)phenyl)-imidazo[1,2-b]pyridazin-6-amine 
• 1025065-79-5 N-((1-ethylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)-imidazo[1,2-b]pyridazin-6-amine 
• 76005-22-6 N²-(1-Ethyl-piperidin-4-ylmethyl)-N⁴-(4-trifluoromethyl-phenyl)-quinazoline-2,4-diamine; hydrochloride 
• 76004-58-5 N²-(3,4-Dichloro-phenyl)-N⁴-(1-ethyl-piperidin-4-ylmethyl)-quinazoline-2,4-diamine; hydrochloride 
• 76005-20-4 N⁴-(3,4-Dichloro-phenyl)-N²-(1-ethyl-piperidin-4-ylmethyl)-quinazoline-2,4-diamine; hydrochloride 
• 76005-21-5 N⁴-(3,5-Dichloro-phenyl)-N²-(1-ethyl-piperidin-4-ylmethyl)-quinazoline-2,4-diamine; hydrochloride 

Relevant academic research and scientific papers

Synthesis and pharmacological evaluation of carboxamide derivatives as selective serotoninergic 5-HT4 receptor agonists

A number of new carboxamide derivatives were synthesized. The affinity of these compounds for the serotoninergic 5-HT4 receptor was evaluated by use of radioligand-binding techniques. The agonistic activity was evaluated as the contractile effect of the ascending colon isolated from guinea-pigs. Among these compounds, 4-amino-5-chloro-2-methoxy-N-[l-[2- [(methylsulfonyl)amino]ethly]-4piperidinylmethyl]benzamide (24) showed a high affinity for the 5-HT4 receptor (Ki = 9.6 nM). Compound 24 displayed a higher affinity for 5-HT4 receptors than the other receptors, including, 5- HT3 and dopamine D2 receptors. In addition, compound 24 was confirmed to be a potent 5-HT4 receptor agonist (ED50 = 7.0 nM). An interaction model between compound 24 and 5-HT4 receptor was proposed.