211685-71-1Relevant academic research and scientific papers
Chemistry of polyhalogenated nitrobutadienes, part 9: Acyclic and heterocyclic nitroenamines and nitroimines from 2-nitroperchlorobuta-1,3-diene
Zapol'skii, Viktor A.,Namyslo, Jan C.,Gjikaj, Mimoza,Kaufmann, Dieter E.
experimental part, p. 843 - 860 (2011/01/11)
Various amino, diamino, aminothio, or benzotriazolo compounds derived from the exceedingly versatile 2-nitroperchlorobutadiene (1) gave structurally interesting and physiologically promising nitro-enamines,-imines,-amidines, and hydrazines as well as ring closure reaction products, e. g. pyrimidines and pyrazoles. Most of these reactions turned out to be highly selective with good to very good yields. The structure of the pyrazole precursor (E,E)-1-(benzotriazol-1-yl)-4,4-dichloro-3-(4-ethoxyphenylamino) -1-(4-ethoxyphenylimino)-2-nitrobut-2-ene (30), due to its exceptional substitution pattern, was evidenced by single-crystal X-ray diffraction analysis.
Azolyl Derivatives of Nitrohalobutadienes. I. Reaction of 1,1-Bis(benzotriazol-1-yl)-2-nitrotrihalo-1,3-butadienes with N-, N,N-, and N,O-Nucleophiles
Zapol'skii,Potkin,Nechai,Kaberdin,Pevzner
, p. 1461 - 1467 (2007/10/03)
Reaction of 1,1-bis(benzotriazol-1-yl)-2-nitrotrihalo-1,3-butadienes with amines (1 : 1) results in the corresponding 1-amino-1-(benzotriazol-1-yl)-2-nitrotrihalo-1,3-butadienes. Reaction of equimolar amount of amine on aminobenzotriazolyl products or of the two-fold excess of amine with bis(benzotriazolyl) compounds affords 1,1-diamino-2-nitrotrihalo-1,3-butadienes. By the reaction of 1,1-bis(benzotriazol-1-yl)-2-nitrotrichloro-1,3-butadiene with N,N- and N,O-binucleophilic reagents derivatives of imidazolidine, oxazolidine, benzimidazoline, and benzoxazoline have been synthesized.
