211691-72-4

Upstream product

• 15186-48-8 2,3-isopropylidene-glyceraldehyde 
• 79364-35-5 (S)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)but-3-en-1-ol 
• 1826-67-1 vinyl magnesium bromide 
• 103795-36-4 (3S,4R)-3-O-benzyl-4,5-O-isopropylidene-3,4,5-trihydroxypentanal 
• 100-44-7 benzyl chloride 
• 87604-53-3 (R)-4-((S)-1-(benzyloxy)but-3-ene-1-yl)-2,2-dimethyl-1,3-dioxypentane 

Downstream Products

• 211692-24-9 4-[(2R,4R)-4-((E)-(S)-7-Acetoxy-1-benzyloxy-hept-3-enyl)-[1,3]dioxolan-2-yl]-benzoic acid methyl ester 
• 211691-96-2 4-[(2S,4R)-4-((E)-(S)-1-Benzyloxy-7-hydroxy-hept-3-enyl)-[1,3]dioxolan-2-yl]-benzoic acid 
• 211691-92-8 4-[(2R,4R)-4-((E)-(S)-1-Benzyloxy-7-hydroxy-hept-3-enyl)-[1,3]dioxolan-2-yl]-benzoic acid 
• 211692-18-1 (2R,5R,6S,8R,9R)-6-Benzyloxy-8,9-dihydroxy-3,13,20-trioxa-tricyclo[13.2.2.1^2,5]icosa-1⁽¹⁸⁾,15⁽¹⁹⁾,16-trien-14-one 
• 211692-06-7 (E)-(2S,5R,6S)-6-Benzyloxy-3,13,20-trioxa-tricyclo[13.2.2.1^2,5]icosa-1⁽¹⁸⁾,8,15⁽¹⁹⁾,16-tetraen-14-one 
• 211692-00-1 (E)-(2R,5R,6S)-6-Benzyloxy-3,13,20-trioxa-tricyclo[13.2.2.1^2,5]icosa-1⁽¹⁸⁾,8,15⁽¹⁹⁾,16-tetraen-14-one 
• 211692-12-5 C₂₄H₂₆O₆ 
• 211691-88-2 Acetic acid (E)-(7S,8R)-7-benzyloxy-8,9-dihydroxy-non-4-enyl ester 
• 211691-82-6 (E)-(S)-7-Benzyloxy-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-hept-4-enoic acid ethyl ester 

Relevant academic research and scientific papers

Ansa macrolides as molecular workbenches: Stereocontrolled syn additions to E olefins

Fixed on an aromatic platform in a conformationally defined way, acyclic (E)-alkenes can be considered gripped on a molecular workbench. The olefinic ansa-macrolides formed in this way are shielded on one face. On epoxidation and dihydroxylation [Eq. (1)] the attack on the double bond takes place diastereoselectively from outside the ring, and the ansa chain can subsequently be cleaved from the workbench by mild hydrogenolysis. Bn = benzyl, NMO = N-methylmorpholin-N-oxide.