5-carboxy-2,3-diphenyl-tetrazolium betaine, also known as XTT, is a water-soluble tetrazolium salt used as a colorimetric assay for measuring cell proliferation and viability. It is reduced by metabolically active cells, particularly in the presence of electron couriers like NADH and NADPH, to form a yellow-colored formazan product. The absorbance of this product can be measured at 450 nm, allowing for the quantification of cell growth and survival. XTT is commonly used in various biological and medical research applications, such as drug screening, toxicity testing, and monitoring immune cell function. Its advantages include ease of use, non-toxicity to cells, and compatibility with a wide range of cell types.
The CAS Registry Mumber 2118-43-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,1,1 and 8 respectively; the second part has 2 digits, 4 and 3 respectively. Calculate Digit Verification of CAS Registry Number 2118-43: (6*2)+(5*1)+(4*1)+(3*8)+(2*4)+(1*3)=56 56 % 10 = 6 So 2118-43-6 is a valid CAS Registry Number.