2118-76-5

Upstream product

• 107657-18-1 3β-hydroxyolean-12-en-11-one acetate 
• 1616-93-9 β-amyrin acetate 

Downstream Products

• 94530-87-7 3β-hydroxy-olean-9(11),12-diene 
• 107657-18-1 3β-hydroxyolean-12-en-11-one acetate 
• 883878-98-6 Acetic acid (3S,4aR,6aS,6bS,8aS,14bS)-4,4,6a,6b,8a,11,11,14b-octamethyl-12,13-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,13,14b-octadecahydro-picen-3-yl ester 

Relevant academic research and scientific papers

Biomimetic oxidation of 3β-hydroxy-olean-12-ene and its acetoxy derivative with monooxygen donors catalyzed by 5,10,15,20-tetraarylporphyrinatoiron(III) chlorides in dichloromethane

The oxidation of 3β-hydroxy-olean-12-ene with monooxygen donors catalyzed by 5,10,15,20-tetraarylporphyrinatoiron(III) chlorides in dichloromethane gives 3β,11α-dihydroxy-olean-12-ene, 3-oxo-olean-12-ene, 3,11-dioxo-olean-12-ene and 3β-hydroxy-olean-9(11),12-diene whereas the oxidation of 3β-acetoxy-olean-12-ene under similar conditions gives 11(-hydroxy-3β-acetoxy-olean-12-ene, 11-oxo-3β-acetoxy-olean-12-ene and 3β-acetoxy-olean-9(11),12-diene in moderate yields.

Triterpenes of Diospyros peregrina Gurke: Partial Synthesis of Olean-9(11),12-dien-3-one and Ursan-9(11),12-dien-3-one (Marsformosanone)

Petrol extract of the fruits of Diospyros peregrina (Ebenaceae) has afforded a pentacyclic triterpene ketone with a homoannular diene system, besides betulin and lupeol.In order to establish the structure of the ketone, partial synthesis of both olean- and ursan-9(11),12-dien-3-ones have been achieved.The structure of the pentacyclic triterpene ketone has been established as marsformosanone (II) from spectral data, chemical reactions and synthesis.The occurrence of marsformosanone in Marsdenia formosana Masamune has been recently reported .