211809-19-7Relevant academic research and scientific papers
4H-1,2,4-pyridothiadiazine 1,1-dioxides and 2,3-dihydro-4H-1,2,4- pyridothiadiazine 1,1-dioxides chemically related to diazoxide and cyclothiazide as powerful positive allosteric modulators of (R/S)-2-amino-3- (3-hydroxy-5-methylisoxazol-4-yl)propionic ac
Pirotte, Bernard,Podona, Tchao,Diouf, Ousmane,De Tullio, Pascal,Lebrun, Philippe,Dupont, Léon,Somers, Fabian,Delarge, Jacques,Morain, Philippe,Lestage, Pierre,Lepagnol, Jean,Spedding, Michael
, p. 2946 - 2959 (2007/10/03)
A series of 4H-1,2,4-pyridothiadiazine 1,1-dioxides and 2,3-dihydro-4H- 1,2,4-pyridothiadiazine 1,1-dioxides bearing various alkyl and aryl substituents on the 2-, 3-, and 4-positions was synthesized and tested as possible positive allosteric modulators o
