211811-93-7

Basic information

• Product Name: N-Acetyl-2-fluoro-L-phenylalanine
• Synonyms: (S)-3-(2-Fluorophenyl)-2-(acetylamino)propanoic acid;(S)-α-(Acetylamino)-2-fluorobenzenepropionic acid;N-Acetyl-2-fluoro-L-phenylalanine
• CAS NO: 211811-93-7
• Molecular Formula: C₁₁H₁₂FNO₃
• Molecular Weight: 225.22
• Mol File: 211811-93-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-Acetyl-2-fluoro-L-phenylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Acetyl-2-fluoro-L-phenylalanine(211811-93-7)
• EPA Substance Registry System: N-Acetyl-2-fluoro-L-phenylalanine(211811-93-7)

Safety Data

• Hazardous Substances Data: 211811-93-7(Hazardous Substances Data)

Upstream product

• 19883-78-4 (S)-2-fluorophenylalanine 
• 108-24-7 acetic anhydride 
• 66574-84-3 N-acetyl-2-fluoro-DL-phenylalanine 
• 297142-51-9 4-(2-fluorophenyl)methylene-2-methyl-5(4H)-oxazolone 
• 944655-93-0 C₁₁H₁₀FNO₃ 
• 446-52-6 2-Fluorobenzaldehyde 

Downstream Products

• 19883-78-4 (S)-2-fluorophenylalanine 

Relevant articles and documents

Asymmetric synthesis of unnatural amino acids and tamsulosin chiral intermediate

An efficient and enantioselective hydrogenation of N-acetylamino phenyl acrylic acids was successfully developed by using ruthenium catalyst. This methodology is important in the field of pharmaceuticals and provides a new process for the preparation of unnatural amino acids and tamsulosin chiral intermediate.

BIOCATALYTICAL TRANSFORMATIONS II. ENANTIOSELECTIVE HYDROLYSIS OF N-ACETYL-FLUORO-PHENYLALANINE-ETHYLESTERS BY LYOPHILISED YEAST

The three nuclear substituted monofluoro D-N-acetylphenylalanine-ethylesters were obtained in excellent yield via enantioselective hydrolysis of their respective racemates by use of lyophilised yeast (Saccharomyces cerevisiae Hansen).