211874-89-4

Upstream product

• 211874-85-0 (1S,9S)-10,10-dimethyl-5-phenyl-6-azatricyclo[7.1.1.0 ^2,7]undeca-2,4,6-triene 

Downstream Products

• 1007589-01-6 (5S,7S,8S)-8-(bromomethyl)-5,6,7,8-tetrahydro-6,6-dimethyl-2-phenyl-5,7-methanoquinoline 
• 211874-92-9 Thioacetic acid S-((1S,8S,9S)-10,10-dimethyl-5-phenyl-6-aza-tricyclo[7.1.1.0^2,7]undeca-2⁽⁷⁾,3,5-trien-8-ylmethyl) ester 
• 211874-91-8 Methanesulfonic acid (1S,8S,9S)-10,10-dimethyl-5-phenyl-6-aza-tricyclo[7.1.1.0^2,7]undeca-2⁽⁷⁾,3,5-trien-8-ylmethyl ester 

Relevant academic research and scientific papers

Development of pinene-derived N,P ligands and their utility in catalytic asymmetric hydrogenation

New diastereomeric N,P-ligands, derived from the natural product (+)-α-pinene, have been synthesized and evaluated in iridium-catalyzed asymmetric hydrogenation. The ligands are tetrahydroquinoline derivatives synthesized directly from commercially available α-pinene utilizing resolution or recrystallization to separate diastereomers. In reduction of a range of different trisubstituted alkenes the catalysts express very different activities ranging from no activity to high activity. One of the catalysts gives good ee values for some substrates. The Royal Society of Chemistry.

Enantioselective addition of diethylzinc to benzaldehyde in the presence of sulfur-containing pyridine ligands

Diastereomerically pure hydroxy and thiol derivatives of (5S,7S)-5,7- methane-6,6-dimethyl-2-phenyl-5,6,7,8-tetrahydroquinoline were prepared and assessed in the enantioselective addition of diethylzinc to benzaldehyde: enantioselectivities up to 62% were