211995-44-7

Upstream product

• 186025-93-4 (E)-3-((S)-2-Phenyl-4,5-dihydro-oxazol-4-yl)-acrylic acid methyl ester 
• 105308-52-9 (R)-2-phenyl-4,5-dihydro-oxazole-4-carboxylic acid methyl ester 
• 5333-86-8 ethyl benzimidate hydrochloride 

Downstream Products

• 97058-12-3 (2R,3S,4S)-2-(hydroxymethyl)pyrrolidine-3,4-diol 

Relevant academic research and scientific papers

The efficient, enantioselective synthesis of aza sugars from amino acids. 1. The polyhydroxylated pyrrolidines

Beginning with (+)-serine or (-)-serine, as appropriate, convenient, high-yield, enantioselective synthesis of all eight stereoisomeric 2-hydroxymethyl-3,4-dihydroxypyrrolidines (the enantiomeric pairs of iminoribitol, -arabinitol, -xylitol, and -lyxitol) can be effected. The absolute configuration of the starting amino acid defines the set of azasugars produced.