211997-75-0Relevant academic research and scientific papers
Asymmetric synthesis of the mC7N core of the manumycin family: Preparation of (+)-MT 35214 and a formal total synthesis of (-)-alisamycin
Macdonald, Gregor,Alcaraz, Lilian,Lewis, Norman J.,Taylor, Richard J. K.
, p. 5433 - 5436 (2007/10/03)
An asymmetric approach to the mC7N epoxyquinone central unit of the manumycin antibiotics is described based on the enantioselective (89% ee) chiral phase transfer epoxidation of a substituted cyclohexenone. The chiral epoxide is employed in the trust syntheses of the title compounds in enantiomerically pure form.
