21204-08-0

Upstream product

• 42569-64-2 (11E)-14,15-bisnor-8α-hydroxy-11-labden-13-one 
• 1117-52-8 6,10,14-trimethyl-5,9,13-pentadecatriene-2-on 
• 25578-83-0 Neoabienol 
• 67987-70-6 2-methyl-2-(2-((1S,4aS,8aS)-5,5,8a-trimethyl-2-methylene-decahydronaphthalen-1-yl)ethyl)-1,3-dioxolane 
• 762-29-8 6,10,14-trimethyl-5,9,13-pentadecatrien-2-one 
• 911397-49-4 C₂₀H₃₄O₃ 
• 4586-83-8 farnesyl acetone acetal 

Relevant academic research and scientific papers

Catalytic epoxypolyene cyclization via radicals: A simple total synthesis of sclareol oxide and its 8-epimer

A short synthesis of sclareol oxide from epoxyfarnesyl acetone in six steps is described. The strategy features a titanocene-catalyzed epoxypolyene cyclization for the construction of the carbocyclic core structure. The exo olefin formed during the termin

Polyene cyclizations using mercury(II) triflate-N,N-dimethylaniline complex-participation by internal nucleophiles

The cyclization of a number of functionalized polyenes with mercuric triflate-N,N-dimethylaniline complex (Nishizawa's reagent) to give bicyclic or tricyclic products has been studied. Suitably positioneal internal nucleophiles, such as carbonyl, hydroxy and β-ketoester groups were found to participate to varying extent, in the termination of these cyclizations.

INVESTIGATION OF THE PRODUCTS OF THE OZONOLYSIS OF NEOABIENOLS

The ozonolysis of a mixture of 13Z- and 13E-neoabienols (I and III) leads, depending on the conditions, either to 8α-hydroxy-14,15-bis-norlabd-11-en-13-one (IV) or to 8α-hydroxdriman-11-oic acid (VI) or to driman-8α,11-diol (VII).Compound (IV) undergoes hydrogenation smoothly with the formation of a mixture of 8α-hydroxy-14,15-bisnorlabdan-13-one (X) and "sclareol oxide" (XI).