21210-43-5

Basic information

• Product Name: (S)-(+)-Methyl mandelate
• Synonyms: METHYL (S)-(+)-MANDELATE;(+)-METHYL (S)-ALPHA-HYDROXY-PHENYL ACETATE;METHYL (S)-ALPHA-HYDROXYPHENYLACETATE;(+)-METHYL L-MANDELATE;METHYL L-(+)-MANDELATE;(+)-L-MANDELIC ACID METHYL ESTER;L-(+)-MANDELIC ACID METHYL ESTER;(S)-(+)-METHYL MANDELATE
• CAS NO: 21210-43-5
• Molecular Formula: C₉H₁₀O₃
• Molecular Weight: 166.17
• EINECS: 145-896-5
• Product Categories: Chiral Building Blocks;Esters (Chiral);Synthetic Organic Chemistry;Chiral Compound;Aromatics;Chiral Reagents
• Mol File: 21210-43-5.mol
• Article Data: 210

Chemical Properties

• Melting Point: 56-58 °C
• Boiling Point: 138 °C / 16mmHg
• Flash Point: >110°C
• Appearance: white crystalline powder
• Density: 1.1097 (rough estimate)
• Vapor Pressure: 0.00715mmHg at 25°C
• Refractive Index: 1.4371 (estimate)
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Sparingly), Methanol (Sparingly)
• PKA: 12.19±0.20(Predicted)
• BRN: 2614741
• CAS DataBase Reference: (S)-(+)-Methyl mandelate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-Methyl mandelate(21210-43-5)
• EPA Substance Registry System: (S)-(+)-Methyl mandelate(21210-43-5)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 21210-43-5(Hazardous Substances Data)

Usage

Chemical Properties

white crystalline powder

Uses

Different sources of media describe the Uses of 21210-43-5 differently. You can refer to the following data:
1. Methyl (S)-(+)-Mandelate (cas# 21210-43-5) is a compound useful in organic synthesis.
2. Methyl (S)-(+)-mandelate may be used in the preparation of (S)-(-)2-hydroxy-1,2,2-triphenylethyl acetate and (α′S)-α′-methoxycarbonylbenzyl (2S,4R)-(+)-1,2,4,5-tetrahydro-4-methyl-7,8-methylenedioxy-5-oxo-3-benzothiepin-2-carboxylate.

General Description

Optically active building block.

InChI:InChI=1/C9H10O3/c1-12-9(11)8(10)7-5-3-2-4-6-7/h2-6,8,10H,1H3/t8-/m0/s1

Upstream product

• 67-56-1 methanol 
• 1074-12-0 phenylglyoxal hydrate 
• 110376-61-9 2-[methyl-((S)-1-methyl-2-phenyl-ethyl)-amino]-ethanethiol 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 108460-23-7 5-carbamoyl 4,7-dihydro thieno<2,3-b>pyridine 
• 121635-41-4 (S)-2-(N-methyl-4,7-dihydrothieno<2,3-b>pyridine-5-carbonyl)aminobutan-1-ol 
• 101031-33-8 N-benzyl-5-(N,N-dimethylcarbamoyl)-3-(hydroxymethyl)-4(R)-methyl-1,4-dihydropyridine 
• 101031-31-6 S-(+)-1-benzyl-3-hydroxymethyl-4-methyl-1,4-dihydropyridine 
• 4358-87-6 (RS)-methyl mandelate 
• 86561-27-5 methyl O-acetylmandalate 
• 263747-35-9 (R)-3-(N,N-dimethylcarbamoyl)-1,2,4-trimethyl-1,4-dihydroquinoline 
• 263747-36-0 (S)-3-(N,N-dimethylcarbamoyl)-1,2,4-trimethyl-1,4-dihydroquinoline 
• 263747-38-2 (4S)-3-piperidinylcarbonyl-1,2,4(S)-trimethyl-1,4-dihydroquinoline 
• 600700-48-9 (3S)-2-(2-methoxyethyl)-3,5-dimethyl-7,8-dimethoxy-1-oxo-1,2,3,4,5,10-hexahydrobenzo[b]-1,6-naphthyridine 

Downstream Products

• 85805-95-4 (S)-Phenyl-phenylacetoxy-acetic acid methyl ester 
• 138380-77-5 Fumarate of (S)-Methyl mandelate 
• 85805-94-3 4-Methyl-pentanoic acid (S)-methoxycarbonyl-phenyl-methyl ester 
• 111975-72-5 (S)-(Methoxycarbonyl)benzyl octanoate 
• 130518-08-0 (S)-(N'-tert-Butoxycarbonyl-hydrazino)-phenyl-acetic acid methyl ester 
• 130518-08-0 (R)-(N'-tert-Butoxycarbonyl-hydrazino)-phenyl-acetic acid methyl ester 
• 111975-73-6 (S)-(+)-(Methoxycarbonyl)benzyl methyl 1,9-nonanedioate 
• 124400-10-8 methyl (S)-(+)-2-phenyl-2-<(phenylmethoxy)acetoxy>-ethanoate 
• 79416-45-8 (+)-methyl (S)-α-acetoxyphenylacetate 
• 142026-00-4 (S)-methyl 2-((p-nitrobenzene)sulfonyl)oxy 2-phenylacetate 
• 20455-46-3 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (S)-methoxycarbonyl-phenyl-methyl ester 
• 180045-21-0 (α'S)-α'-methoxycarbonylbenzyl (2S,4R)-(+)-1,2,4,5-tetrahydro-4-methyl-7,8-methylenedioxy-5-oxo-3-benzothiepin-2-carboxylate 

Relevant articles and documents

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Catalytic enantioselective O-H insertion reactions

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