212143-24-3Relevant academic research and scientific papers
trans-[RuCl2(phosphane)2(1,2-diamine)] and chiral trans-[RuCl2(diphosphane)(1,2-diamine: Shelf-stable precatalysts for the rapid, productive, and stereoselective hydrogenation of ketones
Doucet, Henri,Ohkuma, Takeshi,Murata, Kunihiko,Yokozawa, Tohru,Kozawa, Masami,Katayama, Eiji,England, Anthony F.,Ikariya, Takao,Noyori, Ryoji
, p. 1703 - 1707 (2007/10/03)
A turnover number (TON) of 2400 000 and a turnover frequency (TOF) of 63 s-1 are achieved with the chiral Ru(II) complex 1 (R = p-CH3C6H4) in the asymmetric hydrogenation of acetophenone. Carbonyl-selective asymmetric hydrogenation of α,β-unsaturated ketones proceeds in the presence of these Ru(II) catalysts, and 4-substituted cyclohexanones are selectively converted into cis alcohols.
