212312-33-9 Usage
Uses
Used in Pharmaceutical Industry:
(3aR,8aS)-2[2-(diphenylphosphanyl)phenyl]-3a,8a-dihydroindane[1,2-d]oxazole is used as a potential drug candidate or pharmacological tool for its possible anti-cancer, anti-inflammatory, and anti-microbial properties. Its unique molecular structure allows it to target various biological pathways and mechanisms, offering a wide range of therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, (3aR,8aS)-2[2-(diphenylphosphanyl)phenyl]-3a,8a-dihydroindane[1,2-d]oxazole is used as a key intermediate or building block for the synthesis of more complex organic molecules. Its versatile structure and functional groups make it a valuable component in the development of new pharmaceuticals and specialty chemicals.
Used in Materials Science:
(3aR,8aS)-2[2-(diphenylphosphanyl)phenyl]-3a,8a-dihydroindane[1,2-d]oxazole is also used in materials science for the development of new materials with unique properties. Its chemical and physical characteristics can contribute to the creation of advanced materials for various applications, such as sensors, catalysts, or functional coatings.
Further research is necessary to fully explore the potential pharmacological applications of (3aR,8aS)-2[2-(diphenylphosphanyl)phenyl]-3a,8a-dihydroindane[1,2-d]oxazole and to understand its mechanism of action. This will help in optimizing its use in different industries and maximizing its benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 212312-33-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,2,3,1 and 2 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 212312-33:
(8*2)+(7*1)+(6*2)+(5*3)+(4*1)+(3*2)+(2*3)+(1*3)=69
69 % 10 = 9
So 212312-33-9 is a valid CAS Registry Number.
212312-33-9Relevant academic research and scientific papers
In situ enzymatic screening (ISES) of P,N-ligands for Ni(0)-mediated asymmetric intramolecular allylic amination
Berkowitz, David B.,Shen, Weijun,Maiti, Gourhari
, p. 2845 - 2851 (2007/10/03)
An in situ enzymatic screening (ISES) approach to rapid catalyst evaluation recently pointed to Ni(0) as a new candidate transition metal for intramolecular allylic amination. This led to further exploration of chiral bidentate phosphine ligands for such transformations. Herein, a variety of P,N-ligands are examined for this Ni(0)-chemistry, using a model reaction leading into the vinylglycinol scaffold. On the one hand, an N,N-bis(2-diphenylphosphinoethyl)alkylamine ('PNP') ligand proved to be the fastest ligand yet seen for this Ni(0)-transformation. On the other, phosphinooxazoline (PHOX) ligands of the Pfaltz-Helmchen-Williams variety gave the highest enantioselectivities (up to 51% ee) among P,N-ligands examined.
Chiral phosphinooxazolines with a Bi- or tricyclic oxazoline moiety - Applications in Pd-catalyzed allylic alkylations
Wiese, Burkhard,Helmchen, Guenter
, p. 5727 - 5730 (2007/10/03)
Phosphinooxazolines with a bi- or tricyclic oxazoline moiety are described. In Pd-catalyzed alkylations of 1,3-dimethylallyl acetate with sodium dimethyl malonate enantiomeric excess of up to 89.5 % was obtained. This is the best result so far achieved for this substrate with P,N-chelate ligands.
