212318-70-2Relevant academic research and scientific papers
A versatile approach towards enantiopure α-methyl β-hydroxy ketones. Application to the synthesis of (4R,5S) sitophilure and of its stereoisomers
Delas, Christophe,Szymoniak, Jan,Thery, Nadine,Moise, Claude
, p. 2613 - 2620 (2007/10/03)
Rice weevil pheromone sitophilure ((4R,5S)-5-hydroxy-4-methyl-3- heptanone) and its three diastereomers were synthesized in three steps, starting from 3-(trimethylsilyloxy)-1,3-pentadiene and propionaldehyde. Other optically active α-methyl β-hydroxy ketones can also be synthesized by the reported procedure.
