212322-77-5

Basic information

• Product Name: N-[[2-[[(4-Cyanophenyl)aMino]Methyl]-1-Methyl-1H-benziMidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine
• Synonyms: N-[[2-[[(4-Cyanophenyl)aMino]Methyl]-1-Methyl-1H-benziMidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine;3-(2-(((4-cyanophenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid;N-[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-2-alanine
• CAS NO: 212322-77-5
• Molecular Formula: C₂₅H₂₂N₆O₃
• Molecular Weight: 454.48058
• Product Categories: Aromatics, Heterocycles, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 212322-77-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Solubility: DCM, Methanol
• CAS DataBase Reference: N-[[2-[[(4-Cyanophenyl)aMino]Methyl]-1-Methyl-1H-benziMidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine(CAS DataBase Reference)
• NIST Chemistry Reference: N-[[2-[[(4-Cyanophenyl)aMino]Methyl]-1-Methyl-1H-benziMidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine(212322-77-5)
• EPA Substance Registry System: N-[[2-[[(4-Cyanophenyl)aMino]Methyl]-1-Methyl-1H-benziMidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine(212322-77-5)

Safety Data

• Hazardous Substances Data: 212322-77-5(Hazardous Substances Data)

Usage

Uses

N-[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine is an intermediate in the synthesis of Dabigatran (D100090), an nonpeptide, direct thrombin inhibitor.

Upstream product

• 211915-84-3 3-[[[2-[[(4-cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl](pyridin-2-yl)amino]propionic acid ethyl ester 
• 60-29-7 diethyl ether 

Downstream Products

• 1610758-18-3 C₂₈H₃₁N₇O₃*C₇H₈O₃S 
• 1610758-16-1 C₂₆H₂₇N₇O₃*C₇H₈O₃S 
• 211915-00-3 methyl-3-[[[2-[[[4-[amino[[[(hexyloxy)carbonyl]imino]methyl]]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl](pyridin-2-yl)amino]propionate 
• 1610758-19-4 C₃₅H₄₃N₇O₅ 
• 212322-47-9 1-methyl-2-[N-(4-cyanophenyl)-aminomethyl]-benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-[2-(methanesulphonylaminocarbonyl)-ethyl]-amide 

Relevant articles and documents

Anticoagulant antidotes comprising antibodies that bind dabigatran and/or related compounds and methods of use thereof

The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants.