6,8-DIBROMO-3-CYCLOHEXYL-3,4-DIHYDRO-2(1H)-QUINAZOLINONE is a chemical compound that is identified as an impurity in bromohexine tablets. Bromohexine is a mucolytic drug used for the treatment of respiratory disorders characterized by excessive mucus production. The presence of this impurity in bromohexine tablets may have implications for the drug's safety and efficacy.
21237-84-3
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Basic information
- Product Name: 6,8-DIBROMO-3-CYCLOHEXYL-3,4-DIHYDRO-2(1H)-QUINAZOLINONE
- Synonyms: 6,8-DIBROMO-3-CYCLOHEXYL-3,4-DIHYDRO-2(1H)-QUINAZOLINONE;Ipratropium bromide Impurity L;Bromhexine Related Compound 4;Bromhexine Hydrochloride IMP
- CAS NO:21237-84-3
- Molecular Formula: C14H16Br2N2O
- Molecular Weight: 388.09764
- EINECS: N/A
- Product Categories: N/A
- Mol File: 21237-84-3.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 507.1±50.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.670±0.06 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 12.81±0.20(Predicted)
- CAS DataBase Reference: 6,8-DIBROMO-3-CYCLOHEXYL-3,4-DIHYDRO-2(1H)-QUINAZOLINONE(CAS DataBase Reference)
- NIST Chemistry Reference: 6,8-DIBROMO-3-CYCLOHEXYL-3,4-DIHYDRO-2(1H)-QUINAZOLINONE(21237-84-3)
- EPA Substance Registry System: 6,8-DIBROMO-3-CYCLOHEXYL-3,4-DIHYDRO-2(1H)-QUINAZOLINONE(21237-84-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 21237-84-3(Hazardous Substances Data)
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21237-84-3 Usage
Uses
Used in Pharmaceutical Industry:6,8-DIBROMO-3-CYCLOHEXYL-3,4-DIHYDRO-2(1H)-QUINAZOLINONE is used as an impurity in bromohexine tablets, which are mucolytic drugs for the treatment of respiratory disorders with excessive mucus. The presence of this impurity may affect the drug's safety and efficacy, and it is important to monitor and control its levels during the manufacturing process to ensure the quality and safety of the final product.
Check Digit Verification of cas no
The CAS Registry Mumber 21237-84-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,2,3 and 7 respectively; the second part has 2 digits, 8 and 4 respectively.Calculate Digit Verification of CAS Registry Number 21237-84:
(7*2)+(6*1)+(5*2)+(4*3)+(3*7)+(2*8)+(1*4)=83
83 % 10 = 3
So 21237-84-3 is a valid CAS Registry Number.
21237-84-3Upstream product
21237-84-3Downstream Products
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6,8-DIBROMO-3-CYCLOHEXYL-3,4-DIHYDRO-2(1H)-QUINAZOLINONE
