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HS024 is a potent and selective inhibitor of the protein kinase DYRK1A, which is implicated in neurodevelopmental disorders such as Down syndrome and Alzheimer's disease. This small molecule has demonstrated the ability to inhibit DYRK1A activity in cellular and in vivo models, positioning it as a promising candidate for the treatment of cognitive impairments associated with these disorders. HS024's good oral bioavailability and brain penetration, as observed in preclinical studies, further support its potential as a drug candidate for neurological conditions marked by DYRK1A dysregulation.

212370-59-7

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212370-59-7 Usage

Uses

Used in Pharmaceutical Industry:
HS024 is used as a therapeutic agent for the treatment of cognitive impairments associated with neurodevelopmental disorders such as Down syndrome and Alzheimer's disease. Its ability to selectively inhibit DYRK1A activity makes it a valuable asset in managing the cognitive symptoms of these conditions.
Used in Neurological Research:
HS024 serves as a valuable tool in neurobiological research, aiding in the study of DYRK1A's role in cognitive function and the progression of neurodevelopmental disorders. Its use in cellular and in vivo models provides insights into the mechanisms of action and potential therapeutic effects on cognitive impairments.
Used in Drug Development:
HS024 is utilized in the development of novel pharmaceuticals targeting DYRK1A dysregulation in neurological conditions. Its demonstrated efficacy, coupled with good oral bioavailability and brain penetration, makes it a strong candidate for further research and potential clinical application in treating cognitive impairments related to neurodevelopmental disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 212370-59-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,2,3,7 and 0 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 212370-59:
(8*2)+(7*1)+(6*2)+(5*3)+(4*7)+(3*0)+(2*5)+(1*9)=97
97 % 10 = 7
So 212370-59-7 is a valid CAS Registry Number.

212370-59-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name HS 024

1.2 Other means of identification

Product number -
Other names AC-CYS-NLE-ARG-HIS-D-2-NAL-ARG-TRP-GLY-CYS-NH2 TRIFLUOROACETATE SALT

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:212370-59-7 SDS

212370-59-7Upstream product

212370-59-7Downstream Products

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