212378-89-7

Basic information

• Product Name: (1S,2R)-1-(2-(HYDROXY-3,5-DI-TERT-BUTYL&
• Synonyms: (1S,2R)-1-(2-(HYDROXY-3,5-DI-TERT-BUTYL&;(1S,2R)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol 97%
• CAS NO: 212378-89-7
• Molecular Formula: C24H31NO2
• Molecular Weight: 365.514
• Mol File: 212378-89-7.mol
• Article Data: 12

Chemical Properties

• Melting Point: 128-131 °C
• Boiling Point: 496 °C at 760 mmHg
• Flash Point: 330.3 °C
• Appearance: /
• Density: 1.08g/cm³
• Vapor Pressure: 1.18E-10mmHg at 25°C
• Refractive Index: 1.565
• CAS DataBase Reference: (1S,2R)-1-(2-(HYDROXY-3,5-DI-TERT-BUTYL&(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R)-1-(2-(HYDROXY-3,5-DI-TERT-BUTYL&(212378-89-7)
• EPA Substance Registry System: (1S,2R)-1-(2-(HYDROXY-3,5-DI-TERT-BUTYL&(212378-89-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37
• WGK Germany: 3
• Hazardous Substances Data: 212378-89-7(Hazardous Substances Data)

Usage

Uses

(1S,2R)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol can be used as a ligand to prepare Schiff-base chromium(III) complex, which is used as a catalyst in the synthesis of: Poly(cyclohexene carbonate) by coupling of CO2 and cyclohexene oxide. β-hydroxyenol ethers by asymmetric hetero-ene reaction between aryl aldehydes and 2-methoxypropene.

InChI:InChI=1/C24H31NO2/c1-23(2,3)17-11-16(22(27)19(13-17)24(4,5)6)14-25-21-18-10-8-7-9-15(18)12-20(21)26/h7-11,13-14,20-21,26-27H,12H2,1-6H3/b25-14+/t20-,21+/m1/s1

Upstream product

• 37942-07-7 3,5-di-tert-butyl-2-hydroxybenzaldehyde 
• 7480-35-5 (1S,2R)-1-amino-2-indanol 
• 163061-74-3 (1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol 
• 136030-00-7 (1R,2S)-1-Amino-2-indanol 

Relevant articles and documents

Catalytic asymmetric bromochlorination of aromatic allylic alcohols promoted by multifunctional Schiff base ligands

It was found that the tridentate O,N,O-type Schiff base ligand bearing suitable substituents was a highly effective promoter in the catalytic asymmetric bromochlorination reaction, in which the corresponding aromatic bromochloroalcohols with vicinal halogen-bearing stereocenters were formed with perfect regioselectivity, with moderate to excellent enantioselectivities (up to 93% ee), and with good yields and chemoselectivities.

Synthesis of a chiral fluorescence active probe and its application as an efficient catalyst in the asymmetric Friedel-Crafts alkylation of indole derivatives with nitroalkenes

Novel chiral Zn(ii) complexes were synthesized and these complexes showed fluorescence behaviour. These chiral Zn(ii) complexes were tested in the asymmetric Friedel-Crafts alkylation reaction of indole derivatives with nitroalkenes. In all the cases, the

Synthesis of chiral ligands with multiple stereogenic centers and their application in titanium(iv)-catalyzed enantioselective desymmetrization of meso-epoxides

New chiral ligands, (S,R,S)-1, (S,S,S)-1, (S,S,R)-1, (S,R,R)-1, (R,R,R)-1, (R,R,S)-1, (R,S,S)-1, (R,S,R)-1, (S,R,S)-2, (S,S)-3 and (R,S)-4 with diverse stereogenic centers arising from various diastereomeric combinations of aminoalcohol functionality with