212394-42-8Relevant articles and documents
Microwave-enhanced bismuth triflate-catalyzed epoxide opening with aliphatic amines
Ollevier, Thierry,Nadeau, Etienne
, p. 1546 - 1550 (2008/09/19)
In the presence of a catalytic amount of Bi(OTf)3·4H2O and under microwave irradiation, neat mixtures of epoxides and amines afforded smoothly the corresponding 2-amino alcohols. A wide variety of aliphatic amines were reacted with cycloalkene oxide, styrene oxide, and stilbene oxide. The reaction proceeded rapidly and afforded the 2-amino alcohols in high up to quantitative yields. All products could be obtained without aqueous work-up by simple filtration.
Facile Preparation of Some Highly Hindered Chiral 1,2-Diphenyl-2-(N-monoalkyl)amino Alcohols and N-Benzylbornamine
Jian, Li Sheng,Aiqiao, Mi,Guishu, Yang,Yaozhong, Jiang
, p. 1497 - 1503 (2007/10/02)
The preparation of some novel chiral 1,2-diphenyl-2-(N-monoalkyl)amino alcohols by a facile one-pot procedure and the synthesis of N-benzylbornamine by a reduction process are described herein.