212501-44-5

Basic information

• Product Name: 7-benzyloxy-3,4-dihydro-3-hydroxy-4-(3,4,5-trimethoxyphenyl)-3-isocoumarincarboxylic acid
• Synonyms: 7-benzyloxy-3,4-dihydro-3-hydroxy-4-(3,4,5-trimethoxyphenyl)-3-isocoumarincarboxylic acid
• CAS NO: 212501-44-5
• Molecular Weight: 480.471
• Mol File: 212501-44-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-benzyloxy-3,4-dihydro-3-hydroxy-4-(3,4,5-trimethoxyphenyl)-3-isocoumarincarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 7-benzyloxy-3,4-dihydro-3-hydroxy-4-(3,4,5-trimethoxyphenyl)-3-isocoumarincarboxylic acid(212501-44-5)
• EPA Substance Registry System: 7-benzyloxy-3,4-dihydro-3-hydroxy-4-(3,4,5-trimethoxyphenyl)-3-isocoumarincarboxylic acid(212501-44-5)

Safety Data

• Hazardous Substances Data: 212501-44-5(Hazardous Substances Data)

Upstream product

• 212500-90-8 3-benzyloxy-6-(3,4,5-trimethoxybenzoyl)benzoic acid 
• 212500-83-9 3-benzyloxy-6-(3,4,5-trimethoxybenzoyl)benzaldehyde dimethyl acetal 
• 347423-70-5 3-benzyloxy-6-(3,4,5-trimethoxybenzoyl)benzaldehyde 
• 81418-49-7 5-(benzyloxy)-2-bromobenzaldehyde dimethylacetal 
• 5658-49-1 N,N-dimethyl(3,4,5-trimethoxyphenyl)carboxamide 
• 212501-40-1 7-benzyloxy-4-(3,4,5-trimethoxyphenyl)-3-isocoumarincarboxylic acid 

Downstream Products

• 347423-85-2 methoxymethyl 7-benzyloxy-2-[(4-tert-butoxycarbonylamino)phenyl]-1,2-dihydro-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylate 
• 347423-94-3 ethyl 2-[(4-tert-butoxycarbonylamino)phenyl]-1,2-dihydro-1-oxo-7-(2-pyridylmethoxy)-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylate 
• 1026335-57-8 2-(4-tert-butoxycarbonylamino-phenyl)-1-oxo-7-(pyridin-2-ylmethoxy)-4-(3,4,5-trimethoxy-phenyl)-1,2-dihydro-isoquinoline-3-carboxylic acid methoxymethyl ester 
• 347423-96-5 2-[(4-tert-butoxycarbonylamino)phenyl]-1,2-dihydro-N-methyl-1-oxo-7-(2-pyridylmethoxy)-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxamide 
• 347423-97-6 2-[(4-tert-butoxycarbonylamino)phenyl]-1,2-dihydro-N,N-dimethyl-1-oxo-7-(2-pyridylmethoxy)-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxamide 
• 347423-84-1 ethyl 7-benzyloxy-2-[(4-tert-butoxycarbonylamino)phenyl]-1,2-dihydro-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylate 
• 347423-86-3 7-benzyloxy-2-[(4-tert-butoxycarbonylamino)phenyl]-1,2-dihydro-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxamide 
• 347423-95-4 2-[(4-tert-butoxycarbonylamino)phenyl]-1,2-dihydro-1-oxo-7-(2-pyridylmethoxy)-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxamide 
• 347423-87-4 7-benzyloxy-2-[(4-tert-butoxycarbonylamino)phenyl]-1,2-dihydro-N-methyl-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxamide 
• 347423-88-5 7-benzyloxy-2-[(4-tert-butoxycarbonylamino)phenyl]-1,2-dihydro-N,N-dimethyl-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxamide 
• 212492-68-7 methyl 7-benzyloxy-2-[(4-tert-butoxycarbonylamino)phenyl]-1,2-dihydro-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylate 
• 212498-35-6 methyl 2-(4-((t-butoxycarbonyl)amino)phenyl)-1-oxo-7-(pyridin-2-ylmethoxy)-4-(3,4,5-trimethoxyphenyl)-1,2-dihydroisoquinoline-3-carboxylate 
• 212498-31-2 methyl 2-[(4-tert-butoxycarbonylamino)phenyl]-1,2-dihydro-1-oxo-7-(3-pyridylmethoxy)-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylate 
• 212498-25-4 methyl 2-[(4-tert-butoxycarbonylamino)phenyl]-1,2-dihydro-1-oxo-7-(4-pyridylmethoxy)-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylate 

Relevant articles and documents

Novel, potent, and selective phosphodiesterase 5 inhibitors: Synthesis and biological activities of a series of 4-aryl-1-isoquinolinone derivatives

A novel class of potent and selective phosphodiesterase 5 (PDE5) inhibitors, 4-aryl-1-isoquinolinone derivatives, which have been designed by the comparison of the structure of cGMP and a previously reported 1-arylnaphthalene lignan, was disclosed. Among