21259-33-6

Upstream product

• 109-06-8 α-picoline 
• 88-72-2 1-methyl-2-nitrobenzene 
• 95-53-4 o-toluidine 

Downstream Products

• 117599-00-5 Ru(C₅H₄NC(S)NC₆H₄CH₃)2(OH)H₂O 
• 117599-01-6 Os(C₅H₄NC(S)NC₆H₄CH₃)2(OH)H₂O 
• 1372812-00-4 [Pd(Cl)(κ2-S,N-C6H4CS=N-(2-MePh)(PPh3)] 

Relevant academic research and scientific papers

Synthesis and structure of nickel(II) thiocarboxamide complexes: Effect of ligand substitutions on DNA/protein binding, antioxidant and cytotoxicity

Four low spin d8 nickel(ii) square planar complexes with general formula [Ni(L)2] (where L = monobasic N, S bidentate thiocarboxamides) have been synthesized from the reaction of Ni(OAc)2·4H2O with 2 equivalent

Cationic arene ruthenium(II) complexes bearing N, S chelating thiocarboxamides: Synthesis, structure, characterization and catalytic oxidation of alcohols

A series of conformationally rigid half-sandwich diamagnetic cationic organoruthenium(II) complexes with the general formula [Ru(η6-p- cymene)(AsPh3)(L)] [where, L = pyridine-2-thiocarboxamide ligand] have been synthesized from the reaction of [Ru(η6-p-cymene) Cl2]2 with bidentate thiocarboxamide ligands and AsPh 3 in methanol in 1:2 M ratio. All the arene ruthenium(II) complexes were fully characterized by FT-IR, 1H NMR, and UV-Vis spectroscopy as well as elemental analysis. The solid-state structure of one of the complexes [Ru(η6-p-cymene)(AsPh3)(L4)]BPh4 has been determined by single crystal X-ray crystallography. Further, the catalytic efficiency of one of the complexes (4) has been investigated in the case of oxidation of primary and secondary alcohols into their corresponding aldehydes and ketones in the presence of N- methylmorpholine-N-oxide.

Functionalization of primary ch bonds in picolines toward pyridylthioamides

We report a method for coupling of nitroarenes, 2- or 4-methylazaarenes, and elemental sulfur to afford (2-pyridyl)aryl thioamides. Good tolerance of functionalities was observed, including primary and secondary amines, bromo, iodo, ester, and boronic est

Palladium(ii) thiocarboxamide complexes: Synthesis, characterisation and application to catalytic Suzuki coupling reactions

A simple route to synthesise palladium(ii) complexes from the reaction of N-substituted pyridine-2-thiocarboxamide ligands and PdCl2(PPh 3)2 has been developed. The new complexes are very soluble in common solvents and have been fully characterised (elemental analysis, FT-IR, 1H, 31P, 13C-NMR), including an X-ray diffraction analysis. The molecular structures of all the complexes were determined and reveal the presence of square planar geometry around Pd with little distortion. The complexes were tested in the Suzuki coupling of electronically deactivated aryl and heteroaryl bromides and were found to have much greater activity, without using any promoting additives or phase transfer agent under aerobic conditions. Higher reaction rates are obtained by varying R substituents on the aromatic ring of pyridine-2-thiocarboxamide. The effect of other variables on the cross-coupling reaction, such as temperature, solvent and base, is also reported.