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(3aR,8aS)-2-(isoquinolin-1-yl)-8,8a-dihydro-3aH-indeno[1,2-d]oxazole is a heterocyclic chemical compound with the molecular formula C18H15NO. It features an oxazole ring fused to an indene ring system, with an isoquinoline group attached at the 2-position. This unique structure endows it with potential biological activities and makes it a candidate for applications in medicinal chemistry and drug discovery.

2126902-95-0

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2126902-95-0 Usage

Uses

Used in Medicinal Chemistry:
(3aR,8aS)-2-(isoquinolin-1-yl)-8,8a-dihydro-3aH-indeno[1,2-d]oxazole is used as a compound in medicinal chemistry for its potential to be developed into new drugs. Its unique structure may allow it to interact with biological targets in novel ways, leading to the discovery of new therapeutic agents.
Used in Drug Discovery:
In the field of drug discovery, (3aR,8aS)-2-(isoquinolin-1-yl)-8,8a-dihydro-3aH-indeno[1,2-d]oxazole is utilized as a starting point for the design and synthesis of new pharmaceuticals. Its heterocyclic nature and the presence of multiple ring systems may contribute to its ability to modulate biological pathways relevant to various diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 2126902-95-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,1,2,6,9,0 and 2 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2126902-95:
(9*2)+(8*1)+(7*2)+(6*6)+(5*9)+(4*0)+(3*2)+(2*9)+(1*5)=150
150 % 10 = 0
So 2126902-95-0 is a valid CAS Registry Number.

2126902-95-0Downstream Products

2126902-95-0Relevant academic research and scientific papers

Enantioselective Construction of Trifluoromethoxylated Stereogenic Centers by a Nickel-Catalyzed Asymmetric Suzuki–Miyaura Coupling of Secondary Benzyl Bromides

Huang, Weichen,Wan, Xiaolong,Shen, Qilong

supporting information, p. 11986 - 11989 (2017/09/20)

Trifluoromethoxy-substituted stereogenic centers can be constructed with high enantioselectivity by a nickel-catalyzed Suzuki–Miyaura coupling of readily available α-bromobenzyl trifluoromethyl ethers with a variety of aryl pinacol boronates. The coupling proceeds under mild reaction conditions, and a variety of common functional groups, such as fluoride, chloride, bromide, ester, enolizable ketone, nitro, cyano, amino, and vinyl moieties, were well tolerated. Furthermore, the reaction can be easily scaled up to gram quantities without a decrease in enantioselectivity.

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