212696-38-3

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 141940-37-6 tert-butyl (4-(trifluoromethyl)phenyl)carbamate 

Downstream Products

• 854353-36-9 C₁₃H₁₆F₃NO₃ 
• 693262-92-9 N-[4-(5-chloro-2-methoxy-benzyl)-2-oxo-6-trifluoromethyl-1,2-dihydro-quinolin-3-yl]-C,C,C-trifluoro-methanesulfonamide 
• 693262-87-2 3-amino-4-(5-chloro-2-hydroxy-benzyl)-6-trifluoromethyl-1H-quinolin-2-one 
• 863026-02-2 3-amino-4-(5-chloro-2-methoxy-benzyl)-6-trifluoromethyl-1H-quinolin-2-one 

Relevant academic research and scientific papers

Process for the manufacture of a product of the thiazolo [3,4,5-de] [4,1]benzothiazepine type

Novel processes for the preparation of a compound of the thiazolo[3,4,5-de][4,1]benzothiazepine type and in particular of 2-imino-9-trifluoromethyl-4,5-dihydro-2H,7H-thiazolo[3,4,5-de][4,1]benzothiazepine 6,6-dioxide methanesulfonate and (R,S)-2-imino-9-t

The synthesis and structure-activity relationships of 3-amino-4- benzylquinolin-2-ones: Discovery of novel KCNQ2 channel openers

3-Amino-4-benzylquinolin-2-ones have been identified as a novel class of KCNQ2 channel openers. Synthesis and SAR is described along with their electrophysiological evaluation as activators of the cloned mKCNQ2 channel expressed in Xenopus laevis oocytes.