212699-58-6Relevant academic research and scientific papers
Transfer of 1-alkenyl groups between secondary amines. Relative stability and reactivity of enamines from popular organocatalysts
Carneros, Hector,Sanchez, Dani,Vilarrasa, Jaume
, p. 2900 - 2903 (2014/06/23)
Enamines from 3-methylbutanal and several Pro- and Phe-derived secondary amines were prepared in DMSO-d6, CD3CN, and CDCl 3. For the first time, the relative thermodynamic stabilities of these and other enamines were compared, and rapid exchanges of 1-alkenyl groups were demonstrated. Competition experiments showed that the most favored enamines (without significant steric inhibition of resonance) react more rapidly with electrophiles.
Cyclopropane-Annelated Azaoligoheterocycles by Ti-Mediated Intramolecular Reductive Cyclopropanation of Cyclic Amino Acid Amides
Gensini, Martina,De Meijere, Armin
, p. 785 - 790 (2007/10/03)
Starting from pyrrole- and indole-2-carboxylic acids 5a and 5b, the tri- and tetracyclic N,N-dibenzylcyclopropylamines 7a and 7b have been synthesized in 52 and 33% overall yield, respectively. The synthesis of the enantiopure tetracyclic diamine 10 has b
