21272-28-6

Basic information

• Product Name: 4-[(DIMETHYLAMINO)METHYLENE]-5-PHENYL-2,4-DIHYDRO-3H-PYRAZOL-3-ONE
• Synonyms: 4-[(DIMETHYLAMINO)METHYLENE]-5-PHENYL-2,4-DIHYDRO-3H-PYRAZOL-3-ONE;4-[(dimethylamino)methylidene]-3-phenyl-4,5-dihydro-1H-pyrazol-5-one
• CAS NO: 21272-28-6
• Molecular Formula: C₁₂H₁₃N₃O
• Molecular Weight: 215.25
• Mol File: 21272-28-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-[(DIMETHYLAMINO)METHYLENE]-5-PHENYL-2,4-DIHYDRO-3H-PYRAZOL-3-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(DIMETHYLAMINO)METHYLENE]-5-PHENYL-2,4-DIHYDRO-3H-PYRAZOL-3-ONE(21272-28-6)
• EPA Substance Registry System: 4-[(DIMETHYLAMINO)METHYLENE]-5-PHENYL-2,4-DIHYDRO-3H-PYRAZOL-3-ONE(21272-28-6)

Safety Data

• Hazardous Substances Data: 21272-28-6(Hazardous Substances Data)

Upstream product

• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 4860-93-9 3-phenyl-1H-pyrazol-5-one 

Downstream Products

• 338975-62-5 4-(((4-chlorophenyl)amino)methylene)-3-phenyl-1H-pyrazol-5(4H)-one 
• 338975-59-0 3-phenyl-4-((phenylamino)methylene)-1H-pyrazol-5(4H)-one 
• 857985-87-6 4-(aminomethylene)-3-phenyl-1H-pyrazole-5(4H)-one 
• 1370724-86-9 4-(hydrazinylmethylene)-3-phenyl-1H-pyrazol-5(4H)-one 
• 1370724-84-7 4-phenyl-2H-pyrazolo[4,3-d]isoxazole 

Relevant articles and documents

Pyrazolones as building blocks in heterocyclic synthesis: Synthesis of new pyrazolopyran, pyrazolopyridazine and pyrazole derivatives of expected antifungicidal activity

A series of new pyrazolone and pyrazole derivatives with expected antifungicidal activity have been prepared through the reactions 3-phenyl-1-H-pyrazol-5(4H)-one (3) and 4-(dimethylaminomethylene)-3-phenyl-1H- pyrazol-5(4H)-one (5) with a variety of electrophilic reagents and nucleophilic reagents. The newly synthesized compounds were characterized by IR, 1H NMR, 13C NMR and mass spectral studies.