212752-22-2Relevant academic research and scientific papers
Carbocyclic analogues of N-acetyl-2,3-didehydro-2-deoxy-D-neuraminic acid (Neu5Ac2en, DANA): Synthesis and inhibition of viral and bacterial neuraminidases
Vorwerk, Steffen,Vasella, Andrea
, p. 1732 - 1734 (2007/10/03)
Inhibition of neuraminidases from Influenza A and Salmonella typhimurium is shown by the carbocyclic compound 2, whereas its double-bond isomer 1 hardly binds to these enzymes. The cyclohexenes 1 and 2 were prepared from N-acetyl-D-mannosamine in 18 steps
