212755-77-6

Basic information

• Product Name: METHYL 2-TRIFLUOROMETHYLBENZOYLACETATE
• Synonyms: Methyl 2-(2-trifluoromethylbenzoyl)acetate;3-OXO-3-(2-TRIFLUOROMETHYL-PHENYL)-PROPIONIC ACID METHYL ESTER;METHYL 2-TRIFLUOROMETHYLBENZENOYLACETATE;METHYL 2-TRIFLUOROMETHYLBENZOYLACEATE;METHYL 2-TRIFLUOROMETHYLBENZOYLACETATE;BUTTPARK 18\10-43;Methyl 2-trifluoromethylbenzoylacetate,90%;1-Methyl-2-trifluoromethyl-1H-benzoimidazol-5-ylam
• CAS NO: 212755-77-6
• Molecular Formula: C₁₁H₉F₃O₃
• Molecular Weight: 246.18
• Product Categories: Benzoic acid
• Mol File: 212755-77-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 98-10°C
• Boiling Point: 98-105 °C (0.4 mmHg)
• Flash Point: 114.5 °C
• Appearance: White to light yellow crystal powder
• Density: 1.289 g/cm³
• Refractive Index: 1.481-1.484
• PKA: 9.53±0.46(Predicted)
• CAS DataBase Reference: METHYL 2-TRIFLUOROMETHYLBENZOYLACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-TRIFLUOROMETHYLBENZOYLACETATE(212755-77-6)
• EPA Substance Registry System: METHYL 2-TRIFLUOROMETHYLBENZOYLACETATE(212755-77-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25-25-24
• HazardClass: IRRITANT, IRRITANT-HARMFUL
• Hazardous Substances Data: 212755-77-6(Hazardous Substances Data)

Usage

Chemical Properties

White to light yellow crystal powder

Downstream Products

• 21741-99-1 3-Amino-4-(α,α,α-Trifluor-o-tolyl)furazan 

Relevant articles and documents

Baccatin derivatives and a process for producing the same

The object of the invention is to develop baccatin derivatives useful for preparing taxoid compounds such as paclitaxel and a process for the producing the same. The invention provides baccatin derivatives represented by the general formula (I) as well as a process for producing baccatin derivatives represented by the general formula (I) above, which comprises allowing a baccatin represented by the general formula (II) to react with a β-ketoester in the absence of a catalyst or in the presence of a tin compound or an amine base, preferably under reduced pressure.