212767-79-8Relevant academic research and scientific papers
Synthesis and biological activity of lactones en route to Altohyrtin A
Hermitage, Stephen A.,Murphy, Alison,Roberts, Stanley M.
, p. 1635 - 1638 (2007/10/03)
Lactones 2 and 7 were synthesised and tested against six human tumour cell lines (Pancreas-a, BXPC-3), (Thyroid ca, KAT-4), (Thyroid ca, SW1736), (Lung-NSC, NCI H460), (Pharynx-sq, FADU) and (Prostate, DU-145). Lactone 7 proved inactive, but lactone 2 dis
An efficient protocol for the stereoselective dihydroxylation of ene- ester systems
Hermitage, Stephen A.,Murphy, Alison,Nielsen, Poul,Roberts, Stanley M.
, p. 13185 - 13202 (2007/10/03)
Dihydroxylation of ene ester systems was achieved in good yield and diastereoselectivity under classical catalytic OsO4 and NMO conditions using the intrinsic diastereoselectivity in α-methyl β-OTBS systems. This intrinsic diastereoselection ca
