212829-38-4

Upstream product

• 212829-36-2 Benzoic acid (2R,3R,3aR,5R,6R,7R,7aS)-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-6-phenylselanyl-5-((E)-styryl)-3-triethylsilanyloxy-hexahydro-furo[3,2-b]pyran-7-yl ester 
• 212829-35-1 Benzoic acid (2R,3R,3aS,5R,6R,7R,7aS)-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-6-phenylselanyl-5-((E)-styryl)-hexahydro-furo[3,2-b]pyran-7-yl ester 
• 212829-37-3 Benzoic acid (2R,3R,3aR,5S,7S,7aR)-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-5-((E)-styryl)-3-triethylsilanyloxy-hexahydro-furo[3,2-b]pyran-7-yl ester 

Downstream Products

• 212829-39-5 Acetic acid (2R,3R,3aR,5S,7R,7aR)-3-(tert-butyl-dimethyl-silanyloxy)-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-5-((E)-styryl)-hexahydro-furo[3,2-b]pyran-7-yl ester 

Relevant academic research and scientific papers

The synthesis of octosyl nucleosides based on intramolecular oxyselenation of a conjugated diene

A new stereoselective ring construction for 3,7-anhydrooctofuranosyl nucleoside, which is based on a 6-endo-trig oxyselenation of a conjugate diene, (5'S)-C-(4-phenyl-1,3-butadienyl)uridine, was developed. Because of the appropriate array of functionalities at the 5', 6', and 7'-positions, the cyclization product 14 can be considered to be a versatile synthon for the synthesis of a series of octosyl nucleoside antibiotics. Factors governing the efficiency of this cyclization are also discussed.